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Carvedilol in Treatment of Heart Failure |
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N.
Emukhvari, T. Dekanozishvili |
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Key
words: heart failure, carvedilol. The
aim of the study was to evaluate the effects of 6-month carvedilol therapy
on left systolic and diastolic ventricular functions in patients with
heart failure (HF) caused by myocardial infarction or dilated
cardiomyopathy. Fifty patients (19 women and 31 men, mean age 59.8 ±
8.1) with NYHA-II-IV class of HF and ejection fraction < 30% were
studied. The patients were divided in two groups. The patients of study
group received carvedilol and enalapril, the patients of control group –
enalapril only. If necessary, patients from both groups received diuretics
and nitrates. Results of our study allow us to conclude that carvedilol
significantly improves left ventricular systolic and diastolic functions. |
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