|
D. Metreveli,
N. Bibilashvili, I. Gudushauri, N. Gambashidze, Z. Robitashvili,
K. Miqadze, L. Tigishvili, C. Sajaia
Department of Endocrinology of Georgian State Medical
Academy |
|
Type
2 diabetic patients are at increased risk for CVD.
OBJECTIVE:To determine the prevalence of patients with past
hystory of a myocardium infarction or cerebral strok in newly diagnosed
type 2 diabetic patients in Georgia.
DESIGN: Cross-sectional study.
PATIENTS: Newly diagnosed type 2 diabetic patients (n=648, age (M+SD)
53.9±10.11; female 58 %).
MEASUREMENTS: Blood pressure, body mass index, past history of
CVD.
RESULTS - There was an linear relationship between BMI and age at
diagnosis of type 2 diabetes (p <0.01). Adults with type 2 diabetes were
more obese (BMI 30.0±ÿ5.34 kg/m2) versus control subjects (BMI 27.6±4.51
kg/m2; p <0.001).
Patients, with newly diagnosed type 2 diabetes without an arterial
hypertension had the greater prevalence of a past hystory of myocardium
infarction (13/299 that is 4.3 %), than persons of control group (0/194,
c2=8.66. p=0.003
|
|
Literature:
1. American Diabetes Association. Economic Costs of Diabetes in the U.S.
in 2002. //Diabetes Care. – 2003. - v.26. – N.3. – p.917-932.
2. Лекишвили В.П. Современное представление о диабетической
ретинопатии// Проблемы эндокринологии и гормонотерапии. – 1965. - №3.
–с. 115-122
3. Haffner SM., Stern MP., Hazuda HP., Mitchell BD, Patterson JK.
Cardiovascular risk factors in confirmed prediabetic individuals. Does
the clock for coronary heart disease start ticking before the oncet of
clinical diabetes? //JAMA. – 1990. – v. 21. – N.263. – p.893-898.
4. World Health Organization: Definition, Diagnosis and Classification
of Diabetes Mellitus and its Complications. Report of a WHO
Consultation, Part 1: Diagnosis and Classification of Diabetes Mellutis,
Geneva;., WHO/NCD/NCS/99.2. 1999. –59 p.
5. The Epidemiology of Diabetes Mellitus. An international Perspective/
Ed. J.M.Ekoe., P. Zimmet., R. Williams.-John Wiley&Sons Ltd., 2001. –437
p.
6. Lorenzo C., Okoloise M., Williams K., Stern MP., Haffner SM. The
Metaboloc Syndrome as Predictor of Type 2 Diabetes. The San Antonio
Heart Study.// Diabetes Care. – v.26. – N.3. – p.3153-3159.
7. Reaven G.M. Role of insulin Resistance in Human Disease// Diabetes.
1988. v.37. p. 1597-1607.
8. Hu FB, Stampfer MJ, Haffner SM, Solomon CG, Willet WC, Manson JE.
Elevated Risk of Cardiovascular Disease Prior to Clinical Diagnosis of
Type 2 Diabetes // Diabetes Care. v25. N 7. 2002. p. 1129-1134.
9. Diabetes care and research in Europe: the St Vincent Declaration
action programme. Implementation document/ Ed. Krans H M J., Porta M.,
Keen H., Johansen K.S.// Giornale Italiano Di Diabetologia. Copyright
World Health Organization – 1995.
10. EpiInfo 6. A Word Processing, Database and Statistics Program for
Public Health. Centers For Disease Control & Prevention (CDC), U.S.A.
World Health Organization Geneva, Switzerland. May 25, 1994.
13. Hillier T.A., Pedula K.L. – Characteristics of an Adult Population
With Newly Diagnosed Type 2 Diabetes, The relation of obesity and age of
onset.// Diabetes Care.2001.v.24.N9.-p.1522-1527.
14. Ezenwaka CE, Davis G. Increased risk cardiovascular disease in newly
diagnosed type 2 diabetic patients in a primary health care center in
trinidad.// Diabetes Res. Clin. Pract. – 2000. –v. 50. –N2. –p.137-145.
15. Karlson BW., Herlitz J., Hjalmarson A. Prognosis of acute myocardial
infarction in diabetic and nondiabetic patients.// Diabet Med. – 1994.
–v.10. – N.5. –p.126-130.
16. Young B.A., Maynard C., Bouko E.J. Racial Differences in Diabetic
Nephropathy, Cardiovascular Disease, and Mortality in National
Population of Veterans//Diabetes Care. 2003.v.26. p.2392-2399. |