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Key words: Sepsis, Cardiovascular system, Newborn Babies,
Apicor
According to the modern views, neonatal sepsis is a
clinical syndrome of generalized systemic inflammatory reaction which is
accompanied by bacteriemia and is revealed in the first month of life.
The main purpose of the work was to study the changes of cardiovascular
system and some aspects of the treatment during the sepsis of the
premature newborn babies.
Materials and Methods: Forty-eight newborn babies with the sepsis
diagnose, who were hospitalized in the Pediatric Clinic premature
pathology department of the Tbilisi State Medical University were under
observation. They were examined thoroughly by the clinical-laboratory
examination, whit included electrogardiography, photocardiography and
echocardiography. The clinical analysis was held by the methods of
variant statistics. From the premature newborn babies, diseased with
sepsis, I degree of premature was revealed in 34%, II degree – in 43%,
III degree – in 18.2% and IV degree – in 1.8%. Posthypoxian Cardiopathy
was revealed in 26.5% of premature newborn babies. Non - rheumatic
carditis appeared in 11% of babies in the way of myocarditis or
myopericarditis. Electrocardiography showed the signs of miocardium
diffusive damages, the hypertrophy of both ventricles, the prolongation
of the ventricular systole, deceleration of atrium – ventricular
conduction, cardiac arrhythmia as paroxysmal tachycardia, ventricular
extra systole. Echocardiography showed the existence of echo active
focuses; during the pericarditis on the electrocardiography a low
voltage appeared, the ST segment deviation was revealed above the
isoelectric line, T wave shortening was also shown and an electric axis
was moved to the right.
The treatment was held by the broad spectrum of antibiotics: III-IV
generation of cephalosporin’s combined with aminoglicosides, by
detoxicant and symptomatic therapy. During carditis opposite
instrumentalities of non-specific inflammation were used and during the
severe forms hormonotherapy was used. For the metabolic and albuminous
metabolism correction for the better working of miocardium and in the
purpose of immunomodulation we used antioxidant Apicori. It is a mixture
of two products rich with biologically active components: bees’
production and grape stone.
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